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. 2022 Jun 13;26(8):1650–1664. doi: 10.1002/ejp.1988

FIGURE 1.

FIGURE 1

Patients with osteoarthritis were screened (visit 0) and randomized (visit 1) into 18 weeks of duloxetine followed by 18 weeks of placebo (sequence 1) or 18 weeks of placebo followed by 18 weeks of duloxetine (sequence 2). A 2‐week washout period was conducted between the two treatments. Patients were assessed before (visit 1 and 3) and after (visit 2 and 4) each treatment. Assessments were conducted at each of the four visits. HADS: Hospital anxiety and depression scale, BPI: Brief pain inventory, WOMAC: Western Ontario and McMaster universities osteoarthritis index.