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. 2021 Dec 18;17(10):1269–1280. doi: 10.1080/15592294.2021.2013420

Table 3.

Levels of anthropometric, haematological, and lipid indicators according to the hyperhomocysteinemia (HHcy) criteria.

Parameters Female
Male
Hcy (μmol L–1)
N = 224
< 15.0
N = 16
> 15.0
P-value N = 88
< 15.0
N = 20
> 15.0
P-value
BMI (kg m–2) 24.3 (21.4, 28.0) 30.5 (24.9, 32.0) 0.049 23.7 (21.2, 24.3) 21.0 (19.0, 25.5) 0.655
Body fat (%) 38.2 (31.9, 43.4) 43.3 (38.1, 48.9) 0.087 20.4 (15.6, 25.2) 15.4 (14.2, 28.5) 0.796
Visceral fat (%) 4.0 (3.0, 5.5) 6.0 (5.0, 6.5) 0.033 4.8 (3.0, 7.0) 4.0 (2.0, 8.0) 0.869
Skeletal muscle (%) 25.3 (23.8, 26.8) 24.4 (22.5, 25.6) 0.216 40.5 (37.0, 43.0) 41.2 (35.5, 44.6) 0.869
Erythrocytes (106 µL–1) 4.4 (4.2, 4.6) 4.4 (4.4, 4.5) 0.626 5.0 (5.0, 5.2) 5.3 (5.2, 5.5) 0.069
Haemoglobin (mg dL–1) 12.7 (12.1, 13.3) 12.6 (12.4, 13.0) 0.913 15.0 (14.5, 15.2) 15.6 (14.4, 16.4) 0.436
Haematocrit (%) 36.4 (34.6, 38.3) 35.9 (35.3, 37.7) 0.917 41.6 (40.8, 43.8) 43.4 (41.0, 45.2) 0.285
MCV (fL) 82.9 (80.7, 85.6) 80.9 (80.2, 83.7) 0.283 82.8 (80.4, 86.2) 82.8 (79.8, 84.9) 0.655
MCH (pg) 28.6 (27.8, 29.5) 28.3 (27.5, 29.5) 0.650 29.8 (29.0, 30.3) 29.3 (28.7, 30.4) 0.588
RDW-CV (%) 13.3 (12.9, 13.8) 13.6 (13.1, 14.1) 0.594 13.5 (13.0, 13.8) 12.9 (12.8, 13.0) 0.016
Leucocytes (103 µL–1) 7.2 (6.2, 8.4) 7.2 (5.8, 8.9) 0.733 5.9 (5.2, 7.1) 6.1 (5.6, 6.9) 0.796
Platelets (103 µL–1) 309.0 (284.0, 351.0) 369.0 (289.0, 404.0) 0.133 269.5 (237.0, 311.0) 268.0 (237.0, 324.0) 0.981
TC (mg dL–1) 157.0 (138.0, 177.0) 156.5 (152.0, 166.0) 0.929 147.0 (130.0, 171.0) 149.5 (121.0, 172.0) 0.994
TG (mg dL–1) 79.0 (58.0, 108.0) 73.0 (60.5, 86.0) 0.669 61.0 (52.0, 107.0) 92.5 (69.0, 113.0) 0.285
HDL-C (mg dL–1) 46.0 (39.0, 53.0) 47.0 (35.5, 64.5) 0.703 45.0 (38.0, 53.0) 37.5 (32.0, 43.0) 0.049
LDL-C (mg dL–1) 95.0 (70.0, 117.0) 104.0 (86.5, 155.0) 0.222 82.0 (68.0, 100.0) 93.0 (86.0, 124.0) 0.225
VLDL-C (mg dL–1) 15.8 (11.6, 21.6) 14.6 (12.1, 17.0) 0.669 12.2 (10.4, 21.4) 18.5 (13.8, 22.6) 0.285
TC/HDL ratio 3.4 (2.9, 4.1) 3.0 (2.5, 4.4) 0.545 3.08 (2.6, 4.1) 4.1 (3.9, 4.3) 0.144
LDL/HDL ratio 2.0 (1.5, 2.7) 2.3 (1.8, 2.8) 0.364 1.78 (1.5, 2.4) 2.78 (2.6, 3.0) 0.016
AIP –0.12 (−.27, 0.06) −.26 (−.32, 0.03) 0.456 –0.2 (−.29, −.07) 0.04 (−.06, 0.08) 0.055

BMI, body mass index; MCV, mean corpuscular volume; MCH, mean corpuscular haemoglobin; RDW-CV, red cell distribution width; Hcy, homocysteine; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein (HDL) cholesterol; LDL-C, low-density lipoprotein (LDL) cholesterol; VLDL-C, very-low-density lipoprotein (VLDL) cholesterol; AIP, atherogenic index of plasma. Data are presented as median values and interquartile ranges (IR). The Mann–Whitney U-test was employed to compare the distribution between groups. Statistical significance was set at P < 0.05.