TABLE 4.
Analysis of compositions of microbiomes with bias correction test for difference in absolute abundance of bacteria (species level) between participants reporting often or always gum bleeding (n = 43) or sometimes (n = 135) compared to those who never or rarely bleed from the gums (n = 267), adjusted for age, gender, smoking, and body mass index
| LFC (SE) | p | |
|---|---|---|
| Bacteria taxa (species [P: phylum]) differences between those reporting often or always to bleed from the gums compared to never/rarely gum bleeding | ||
| Actinomyces graevenitzii (P: Actinobacteria) | −0.07 (0.14) | .00 |
| Actinomyces massiliensis (P: Actinobacteria) | −0.46 (0.29) | .00 |
| Actinomyces odontolyticus (P: Actinobacteria) | −0.32 (0.25) | .00 |
| Actinomyces sp. HMT 169 (P: Actinobacteria) | −2.10 (0.39) | .00 |
| Actinomyces sp. HMT 171 (P: Actinobacteria) | −1.54 (0.37) | .01 |
| Actinomyces sp. HMT 448 (P: Actinobacteria) | −1.25 (0.30) | .01 |
| Scardovia wiggsiae (P: Actinobacteria) | −0.94 (0.12) | .02 |
| Corynebacterium durum (P: Actinobacteria) | −1.55 (0.39) | .00 |
| Dermabacter hominis (P: Actinobacteria) | −0.65 (0.10) | .00 |
| Microbacterium flavescens (P: Actinobacteria) | −0.70 (0.15) | .00 |
| Microbacterium ginsengisoli (P: Actinobacteria) | −0.79 (0.17) | .00 |
| Propionibacteriaceae [G‐2] bacterium HMT 192 (P: Actinobacteria) | −0.75 (0.17) | .00 |
| Atopobium parvulum (P: Actinobacteria) | −1.23 (0.23) | .00 |
| Bacteroidetes [G‐5] bacterium HMT 511 (P: Bacteroidetes) | 1.77 (0.39) | .00 |
| Porphyromonas endodontalis (P: Bacteroidetes) | 2.21 (0.35) | .00 |
| Prevotella histicola (P: Bacteroidetes) | −1.06 (0.21) | .00 |
| Prevotella intermedia (P: Bacteroidetes) | −1.90 (0.58) | .00 |
| Prevotella salivae (P: Bacteroidetes) | −1.26 (0.23) | .00 |
| Prevotella sp. HMT 306 (P: Bacteroidetes) | −1.00 (0.13) | .00 |
| Prevotella sp. HMT 313 (P: Bacteroidetes) | −0.73 (0.15) | .00 |
| Lysinibacillus fusiformis (P: Firmicutes) | −0.69 (0.10) | .00 |
| Streptococcus infantis clade 638 (P: Firmicutes) | −1.03 (0.24) | .01 |
| Streptococcus intermedius (P: Firmicutes) | −1.90 (0.42) | .00 |
| Streptococcus mutans (P: Firmicutes) | −1.23 (0.27) | .00 |
| Streptococcus parasanguinis clade 411 (P: Firmicutes) | −1.11 (0.26) | .01 |
| Streptococcus salivarius (P: Firmicutes) | −1.10 (0.27) | .02 |
| Streptococcus sanguinis (P: Firmicutes) | −1.25 (0.30) | .01 |
| Streptococcus sp. HMT 066 (P: Firmicutes) | −0.93 (0.20) | .00 |
| Catonella morbi (P: Firmicutes) | 0.75 (0.17) | .00 |
| Oribacterium sinus (P: Firmicutes) | −0.83 (0.14) | .00 |
| Stomatobaculum longum (P: Firmicutes) | −0.92 (0.16) | .00 |
| Stomatobaculum sp. HMT 097 (P: Firmicutes) | −0.67 (0.15) | .00 |
| Peptostreptococcaceae bacterium HMT 081 (P: Firmicutes) | 2.10 (0.37) | .00 |
| Dialister pneumosintes (P: Firmicutes) | 1.70 (0.40) | .00 |
| Bosea vestrisii (P: Proteobacteria) | −1.03(0.24) | .01 |
| Novosphingobium panipatense (P: Proteobacteria) | −0.61 (0.11) | .00 |
| Neisseria bacilliformis (P: Proteobacteria) | −1.45 (0.33) | .00 |
| Hemophilus parainfluenzae (P: Proteobacteria) | −1.63 (0.40) | .01 |
| Haemophilus sputorum (P: Proteobacteria) | −0.74 (0.18) | .01 |
| Treponema denticola (P: Spirochaetes) | 1.94 (0.47) | .01 |
| Fretibacterium fastidiosum (P: Synergistetes) | 1.73 (0.38) | .00 |
| Fretibacterium sp. HMT 360 (P: Synergistetes) | 1.94 (0.42) | .00 |
| Bacteria taxa (species [P: phylum]) differences between those reporting sometimes to bleed from the gums compared to never/rarely gum bleeding | ||
| Streptococcus intermedius (P: Firmicutes) | −1.06 (0.25) | .00 |
| Peptostreptococcaceae bacterium HMT 081 (P: Firmicutes) | −0.19 (0.23) | .00 |
| Treponema sp. HMT 270 (P: Spirochaetes) | 0.57 (0.13) | .01 |
Note: Results given by LFC (natural log), SE, and adjusted p‐values.
Abbreviation: LFC, log fold‐change.