Table 5.
The Top 8 network topology parameters of the degree value of the PPI network graph.
| Gene | Protein name | Degree | BC | CC | TC |
|---|---|---|---|---|---|
| AKT1 | AKTSerine/ThreonineKinase1 | 39 | 0.096052 | 0.842105 | 0.439637 |
| TP53 | TumorProteinP53 | 38 | 0.039903 | 0.813559 | 0.464726 |
| IL6 | Interleukin6 | 38 | 0.082867 | 0.813559 | 0.44065 |
| VEGFA | VascularEndothelialGrowthFactorA | 36 | 0.029326 | 0.786885 | 0.479314 |
| EGFR | EpidermalGrowthFactorReceptor | 34 | 0.026021 | 0.761905 | 0.48373 |
| CASP3 | Caspase3 | 33 | 0.023723 | 0.75 | 0.49323 |
| STAT3 | SignalTransducerAndActivatorOfTranscription3 | 32 | 0.017903 | 0.738462 | 0.50133 |
| TNF | TNFReceptorSuperfamilyMember1A | 32 | 0.035114 | 0.738462 | 0.484043 |
AKT1 = recombinant Human Protein Kinase, BP = biological processes, CASP3 = Apoptosis-Related Cysteine Peptidase, CC = closeness centrality, EGFR = epidermal growth factor receptor, IL6 = interleukin-6, PPI = protein-protein interaction, STAT3 = signal transducer and activator of transcription 3, TC = topological coefficient, TNF = Tumor Necrosis Factor, TP53 = Tumor Protein p53, VEGFA = vascular endothelial growth factor.