Figure 7.

Satb1^m1Anu/m1Anu mice exhibit increased frequencies of CD4⁺ and CD8⁺ FOXP3⁺ T cells. The (a, b) proportion and (c, d) total numbers of CD4⁺ and CD8⁺ cells with T regulatory (T_reg) cells phenotypes (see Supplementary figure 7 for gating of FOXP3^hiGITR^hi and FOXP3^int subsets) from the spleens of uninfected wild‐type (WT) and Satb1^m1Anu/m1Anu mice (a–d, top panels) or from mice 14 days after primary A/HKx31 infection (a–d, bottom panels). Error bars show mean ± s.d. of three or five mice per group from three independent experiments. Unpaired Student's t‐tests were used. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001. SATB1, special AT‐binding protein 1.