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. 2022 Mar 10;18(10):2443–2458. doi: 10.1080/15548627.2022.2038999

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Figure 7. — Lamp1 mutant larvae have altered lipid levels. (A) Sterol levels are increased in Lamp1^e879 mutants, an effect that is partially rescued by a duplication including Lamp1 (Dp). Two-tailed T-tests. (B-D) Compared to wildtype (B), Lamp1^e879 mutant larvae (C) accumulated unesterified sterols as revealed by filipin staining (quantified in D). One-way Anova (Dunnett) P < 0.0001. (E) Triacylglycerols (TAG) are unaffected. (C) Levels of larval DAGs and their indicated subclasses in Lamp1^e879 mutants. Note the rescue by Lamp1^Dp. One-way ANOVA (Tukey correction) significance levels are indicated below the X-axis. Unless indicated, changes are not significant (ns). * P < 0.05; ** P < 0.01; **** P < 0.0001.