Table 1.

Description of some secreted proteins involved in various biological processes of Verticillium dahliae.

Secreted protein	Function description	Cell wall degradation	Host immunity manipulation	Hormone homeostasis Interference	Cytotoxicity	Oxidative stress neutralization	Fungal nutrition	Morphological development	Microbiome manipulation	Others	Host molecular target	Reference
VD18.5	Phytotoxic protein				√							Palmer, Saleeba & Lyon (2005)
VDH1	Class II hydrophobin gene							√				Klimes & Dobinson (2006)
VdEg‐1	Endoglucanase 1	√						√				Maruthachalam et al. (2011)
VdAve1	Avirulence gene of race 1		√	√					√		Ve1	de Jonge et al. (2012); Snelders et al. (2020)
VdNLP1	Necrosis‐ and ethylene‐inducing‐like protein				√			√			GIPC sphingolipids	Zhou et al. (2012); Santhanam et al. (2013)
VdNLP2	Necrosis‐ and ethylene‐inducing‐like protein				√						GIPC sphingolipids	Zhou et al. (2012); Santhanam et al. (2013)
VdSSP1	Cell wall degradation related protein	√					√					Liu et al. (2013)
VdISC1	Isochorismatase		√	√							Isochorismate	Liu et al. (2014)
VdPL3.1	Pectin lyase	√										Chen et al. (2016)
VdPL3.3	Pectin lyase	√										Chen et al. (2016)
Vd2LysM	Chitin‐binding lysin motif		√					√			Plant chitinases	Kombrink et al. (2017)
VdASP F2	Allergen Asp F2‐like protein							√				Xie, Li & Yang (2017)
VdCBM1	Cellulose binding module 1	√	√	√								Gui et al. (2017, 2018); Wang et al. (2020a)
VdCP1	Cerato‐platanin protein 1		√	√							Plant chitinases	Zhang et al. (2017a)
VdEG1	GH12 domain‐containing protein	√	√	√								Gui et al. (2017)
VdEG3	GH12 domain‐containing protein	√	√	√								Gui et al. (2017)
VdSCP7	Small cysteine‐rich protein		√	√								Zhang et al. (2017b)
VdPEL1	Pectate lyase	√	√	√								Yang et al. (2018)
VdPL1	Polysaccharide lyase	√										Zhang et al. (2018)
VdCUT11	Cutinase	√	√	√								Gui et al. (2018)
PevD1	Alt a 1 family protein		√	√							GhPR5, ORE1	Zhang et al. (2021); Liang et al. (2018)
VdSCP41	Small cysteine‐rich protein		√	√							CBP60g and SARD1	Qin et al. (2018)
VdOCH1	Alpha‐1, 6‐mannosyltransferase						√	√				Zhang et al. (2019b)
VdPDA1	Polysaccharide deacetylase		√	√							Chitin oligomer	Gao et al. (2019)
VdSSEP1	Secretory Ser protease 1		√	√						√	Plant chitinases	Han et al. (2019)
VdSCP27	Small cysteine‐rich protein		√	√								Wang et al. (2020a)
VdSCP113	Small cysteine‐rich protein		√	√								Wang et al. (2020a)
VdSCP126	Small cysteine‐rich protein		√	√								Wang et al. (2020a)
VdSOD3	Superoxide dismutase					√						Tian et al. (2020)
VdAMP2	Antimicrobial effector								√			Snelders et al. (2020)
VdSOD5	Superoxide dismutase					√						Tian et al. (2021a)
VdSOD1	Cu/Zn superoxide dismutase					√						Tian et al. (2021b)
Av2	Avirulence gene of race 2		√								V2	Chavarro‐Carrero et al. (2021)
VdEIX3	Ethylene‐inducing xylanase	√	√	√							EIX2	Yin et al. (2021)
VdXyn4	Xylanase	√	√	√	√		√					Wang et al. (2021a)
VDAL	Asp f2‐like protein		√								PUB25/26	Ma et al. (2021)
VdAMP3	Antimicrobial effector								√			Snelders et al. (2021)
VdR3e	Avirulence gene of race 3		√									Wang et al. (2021b)
VdRTX1	Ribonuclease		√							√		Yin et al. (2022)

CBP60g, calmodulin binding protein 60 family member g; EIX2, leucine‐rich repeat receptor‐like protein; GIPC, glycosylinositol phosphorylceramide; ORE1, A senescence‐associated NAC transcription factor; PR5, pathogenesis‐related protein 5 (PR5)‐like protein; PUB25/26, plant U‐box 25/26; SARD1, systemic acquired resistance deficient 1; Ve1, leucine‐rich repeat receptor‐like protein.