TABLE 3.
Proposed diagnostic indices and their associated statistics
| Cohort/cytological assessment | Diagnostic model | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) | AUC (%) |
|---|---|---|---|---|---|---|---|
| Cytological assessment | — | 66.23 | 88.31 | 85 | 72.34 | 77.27 | 84.4 |
| Cell‐block |
Ki‐67 OLP/OLL <20.09 |
100 | 100 | 100 | 100 | 100 | 100 |
|
BAX OLP/OLL >101.22 |
93.55 | 90 | 93.55 | 90 | 92.16 | 91.8 | |
| Tissue‐block |
Ki‐67 OLP/OLL <86.16 |
100 | 100 | 100 | 100 | 100 | 100 |
|
BAX OLP/OLL >188.9 |
88.24 | 100 | 100 | 66.67 | 90.48 | 94.1 | |
| Regression models | Ki‐67/BAX OLP/OLL <1.59 | 100 | 100 | 100 | 100 | 100 | 100 |
| Cytology/BAX OLP/OLL <1.51 | 90 | 100 | 100 | 93.1 | 95.74 | 95 |
Abbreviations: AUC, area under the curve; NPV, negative predictive value; PPV, positive predictive value.