Table 4.
GO enrichment analysis of CD48 via DAVID.
| Gene | GO term and function | Fold enrichment |
FDR | p value |
|---|---|---|---|---|
| CD48 | GOTERM_BP | 1.0 | 1.0 | |
| GO:0002819, regulation of adaptive immune response | 137.6 | |||
| GO:0006952, defense response | 250.6 | |||
| GO:0042110, T cell activation | 357.3 | |||
| GO:0007165, signal transduction | 14.5 | |||
| GO:0045576, mast cell activation | 2099.0 | |||
| GO:0050900, leukocyte migration | 137.6 | |||
| GOTERM_CC | ||||
| GO:0005886, plasma membrane | 4.4 | |||
| GO:0005887, integral component of plasma membrane | 12.9 | |||
| GO:0009897, external side of plasma membrane | 85.6 | |||
| GO:0016020, membrane | 8.3 | |||
| GO:0016021, integral component of membrane | 3.5 | |||
| GO:0031225, anchored component of membrane | 161.3 | |||
| GO:0043234, protein complex | 44.2 | |||
| GO:0045121, membrane raft | 88.5 | |||
| GO:0046658, anchored component of plasma membrane | 650.9 | |||
| GO:0070062, extracellular exosome | 6.5 | |||
| GOTERM_MF | ||||
| GO:0003823, antigen binding | 163.9 | |||
| GO:0004872, receptor activity | 77.8 | |||
| GO:0005515, protein binding | 1.9 | |||
BP = biological process, CC = cellular component, DAVID = database for annotation, visualization and integrated discovery, FDR = false discovery rate, GO = gene ontology, MF = molecular function.