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. 2022 May 24;151(7):993–1004. doi: 10.1002/ijc.34050

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© 2022 The Authors. International Journal of Cancer published by John Wiley & Sons Ltd on behalf of UICC.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Histogram of (A) S5 score and (B) genotype by histological outcome (no biopsy within 12 months, <CIN2, CIN2, CIN3/AIS and cancer) for hrHPV positive women with screening cytology. Percentages add to 100% in each histology group.

A histogram showing (A) the distribution of S5 scores (categorised) by histology (no biopsy within 12 months, <CIN2, CIN2, CIN3/AIS and cancer) and (B) distribution of genotypes (grouped) by histology. Upper 95% confidence interval (CI) are plotted. Percentage of S5 score and genotype sum to 100% within each histology group. Higher histology categories are associated with greater proportions of higher S5 score and more higher‐risk genotypes.

AIS, adenocarcinoma in situ; CIN2, cervical intraepithelial neoplasia grade 2; CIN3, cervical intraepithelial neoplasia grade 3; hrHPV, high‐risk human papillomavirus