Figure 6.

Probiotics reduce ARGs in COVID-19 patients after viral clearance. (a) Schematic overview of the study design, depicting the total number of samples and participants from whom data were available. The horizontal bars represent the sample collected at specific time point. (b) Bray–Curtis dissimilarities clearly separated the resistome at baseline and that after probiotics supplementation in subjects taking SIM01. The dynamics of the observed ARG types (c), subtypes (d), and abundance (e) in subjects taking SIM01 from baseline to week 12. *P < .05, **P < .01, ***P < .001, ****P < .0001, Kruskal–Wallis and Dunn’s tests (all panels).