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. 2022 Sep 28;23(1):1–15. doi: 10.1080/15384047.2022.2125748

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — BRD4 could be a good target for Acute Myeloid Leukemia (AML). (a) BRD4 mRNA expression was characterized in different cancer cell lines (generated from the web site: Broad Cancer Cell Line Encyclopedia: https://depmap.org/portal/download/). High expression of BRD4 was observed in AML cell lines. (b) According to the R2 database (https://hgserver1.amc.nl/cgi-bin/r2/main.cgi, Bohlander-422-fRMA-u133a; source:GEO ID, gse37642), the overall survival rate of high BRD4 expression with AML is lower than that of patients with low BRD4 expression. (c)According to the GEPIA2 database (http://gepia2.cancer-pku.cn/#index), the overall survival rate of high BRD4 expression in patients with AML is lower than that of patients with low BRD4 expression.