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. 2022 Sep 28;23(1):1–15. doi: 10.1080/15384047.2022.2125748

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — MZ1 suppresses the proliferation of AML cells. (a) Cell viability and IC50 values of NB4, Kasumi-1, MV4-11, and K562 cells after treatment with different concentrations of MZ1 for 48 h. (b) Basal BET protein levels of NB4, Kasumi-1, MV4-11, and K562 cells. (c) Morphology of NB4, Kasumi-1, MV4-11, and K562 cells treated with DMSO or MZ1. (d) Cell growth curves of NB4, Kasumi-1, MV4-11, K562 cells treated with DMSO or MZ1 for 7 days. Each concentration was tested in triplicate and independently performed at least three times. *p < .05, **p < .01, ***p < .001, ****p < .0001.