TABLE 3.

Mean (±SD) serum cytokine measurements at Day (D)0 and D28 including monocyte chemotactic protein‐1 (MCP‐1), interleukin (IL)‐6, IL‐8, IL‐31 and IL‐34. No significances in treatment, time or treatment × time were noted

Cytokine	Treatment D0	Treatment D28	Placebo D0	Placebo D28	Time	P Treatment	Treatment × time
MCP‐1 (pg/ml)	376.5 ± 404.5	325.8 ± 215.3	228.7 ± 123.9	258.4 ± 147.8	0.86	0.08	0.51
IL‐6 (pg/ml)	17.5 ± 8.7	17.6 ± 9.2	17.9 ± 17.4	18.1 ± 17.4	0.81	0.42	0.94
IL‐8 (pg/ml)	2778 ± 2938	2497 ± 2246	1802 ± 1697	1857 ± 1715	0.82	0.37	0.61
IL‐31 (pg/ml)	321.4 ± 238.4	386.9 ± 448.4	310.7 ± 248.5	364.3 ± 258.7	0.42	0.75	0.93
IL‐34 (pg/ml)	29.3 ± 28.4	29.2 ± 28.7	24.6 ± 10.3	23.6 ± 11.3	0.71	0.11	0.72