FIGURE 1.

Cabotegravir pharmacokinetic model: two‐compartment model with first‐order oral and LA IM absorption and elimination. CL, central clearance; F_oral, absolute bioavailability of oral tablet; F_LA, absolute bioavailability of LA IM injection; IM, intramuscular; KA_oral, absorption rate constant of oral tablet; KA_LA, absorption rate constant of LA IM injection; LA, long‐acting; Q, intercompartment clearance; V2, central compartment volume of distribution; V3, peripheral compartment volume of distribution