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. Author manuscript; available in PMC: 2023 Jul 14.
Published in final edited form as: Chem. 2022 Jul 1;8(7):1805–1821. doi: 10.1016/j.chempr.2022.06.005

Scheme 2. C─O Bond Activation.

Scheme 2.

(A) Hydrogenation of epoxide

(B) Precision deuteration of epoxide

(C) Regiodivergent synthesis of N-heterocycles

(D) Isomerization of epoxide via bimetallic catalysis

(E) Reductive initiated benzylic C─H oxidation

(F) Reductive activation of alcohol