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. 2022 May 16;39(9):e14866. doi: 10.1111/dme.14866

TABLE 4.

Transitions between medication groups

Medication group Stability, annual range (%) Most common transitions, annual range (%) Other transitions per group, max (%)
No medication 79–86

Metformin (3–8),

Gliptins (1–6)

2.1
Metformin only 88–91

Gliptins (3–8),

SGLT2‐i (0–5)

1.6
Gliptins without SGLT2‐i or GLP−1 RA or insulin 81–88

Long‐acting insulin (4–8),

SGLT2‐i (1–11)

2.0
SGLT2‐i without GLP−1 RA or insulin 84–96 Long‐acting insulin (4–8) 3.5
GLP−1 RA without insulin 83–91 Long‐acting insulin (4–12), Gliptins (0–5) 2.7
Long‐acting insulin 90–93 Short‐acting insulin (5–7) 1.3
Short‐acting insulin 90–94 Long‐acting insulin (5–7) 1.5
Other 67–75

Gliptins (8–19),

Long‐acting insulin (2–6),

Metformin only (3–5),

SGLT2‐i (0–9),

No medication (0–8)

3.4