TABLE 3.
Incidence of AEs and ADRs during colonoscopy and gastroscopy
| Ciprofol (n = 144) | Propofol (n = 145) | P value | |||
|---|---|---|---|---|---|
| Subjects (n, %) | Events (n) | Subjects (n, %) | Events (n) | ||
| AEs | 109 (75.7) | 211 | 100 (69.0) | 202 | 0.201 |
| ADRs | 41 (28.5) | 56 | 35 (24.1) | 54 | 0.403 |
| Severity of AEs | 0.603 | ||||
| Mild | 101 (70.1) | 179 | 94 (64.8) | 175 | |
| Moderate | 24 (16.7) | 30 | 20 (13.8) | 26 | |
| Severe | 2 (1.4) | 2 | 1 (0.7) | 1 | |
| Severity of ADRs | 0.692 | ||||
| Mild | 34 (23.6) | 46 | 33 (22.8) | 47 | |
| Moderate | 9 (6.3) | 10 | 7 (4.8) | 7 | |
| Severe | 0 (0.0) | 0 | 0 (0.0) | 0 | |
| Significant AEs | 13 (9.0) | 13 | 6 (4.1) | 7 | 0.094 |
| AESI | 21 (14.6) | 21 | 19 (13.1) | 22 | 0.716 |
| ADRSI | 21 (14.6) | 21 | 19 (13.1) | 22 | 0.716 |
| SAEs | 1 (0.7) | 1 | 1 (0.7) | 1 | 1.000 |
| SADRs | 0 (0.0) | 0 | 0 (0.0) | 0 | ‐ |
Note: ADRs, adverse drug reactions; AEs, adverse events; ADRSI, adverse drug reactions of special interest; AESI, adverse events of special interest; SADRs, serious adverse drug reactions; SAEs, serious adverse events.