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. 2022 Jun 10;131(2):138–148. doi: 10.1111/bcpt.13761

TABLE 4.

Adverse drug reactions (ADRs, >2%) during colonoscopy and gastroscopy

ADRs, n (%) Ciprofol (n = 144) Propofol (n = 145)
All Mild Moderate Severe All Mild Moderate Severe
Elevation of conjugated bilirubin 4 (2.8) 4 (2.8) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Prolongation of QT interval 3 (2.1) 3 (2.1) 0 (0.0) 0 (0.0) 2 (1.4) 2 (1.4) 0 (0.0) 0 (0.0)
Respiratory depression 4 (2.8) 2 (1.4) 2 (1.4) 0 (0.0) 8 (5.5) 8 (5.5) 0 (0.0) 0 (0.0)
Apnea 2 (1.4) 2 (1.4) 0 (0.0) 0 (0.0) 6 (4.1) 6 (4.1) 0 (0.0) 0 (0.0)
Hypoxemia 4 (2.8) 2 (1.4) 2 (1.4) 0 (0.0) 7 (4.8) 5 (3.4) 3 (2.1) 0 (0.0)
Pain on injection 7 (4.9) 7 (4.9) 0 (0.0) 0 (0.0) 76 (52.4) 76 (52.4) 0 (0.0) 0 (0.0)
Sinus bradycardia 3 (2.1) 0 (0.0) 3 (2.1) 0 (0.0) 2 (1.4) 0 (0.0) 2 (1.4) 0 (0.0)
Hypotension 18 (12.5) 16 (11.1) 2 (1.4) 0 (0.0) 11 (7.6) 9 (6.2) 2 (1.4) 0 (0.0)
Dizziness 6 (4.2) 6 (4.2) 0 (0.0) 0 (0.0) 9 (6.2) 9 (6.2) 0 (0.0) 0 (0.0)

Note: ADRs, adverse drug reactions; AEs, adverse events.