TABLE 4.
ADRs, n (%) | Ciprofol (n = 144) | Propofol (n = 145) | ||||||
---|---|---|---|---|---|---|---|---|
All | Mild | Moderate | Severe | All | Mild | Moderate | Severe | |
Elevation of conjugated bilirubin | 4 (2.8) | 4 (2.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Prolongation of QT interval | 3 (2.1) | 3 (2.1) | 0 (0.0) | 0 (0.0) | 2 (1.4) | 2 (1.4) | 0 (0.0) | 0 (0.0) |
Respiratory depression | 4 (2.8) | 2 (1.4) | 2 (1.4) | 0 (0.0) | 8 (5.5) | 8 (5.5) | 0 (0.0) | 0 (0.0) |
Apnea | 2 (1.4) | 2 (1.4) | 0 (0.0) | 0 (0.0) | 6 (4.1) | 6 (4.1) | 0 (0.0) | 0 (0.0) |
Hypoxemia | 4 (2.8) | 2 (1.4) | 2 (1.4) | 0 (0.0) | 7 (4.8) | 5 (3.4) | 3 (2.1) | 0 (0.0) |
Pain on injection | 7 (4.9) | 7 (4.9) | 0 (0.0) | 0 (0.0) | 76 (52.4) | 76 (52.4) | 0 (0.0) | 0 (0.0) |
Sinus bradycardia | 3 (2.1) | 0 (0.0) | 3 (2.1) | 0 (0.0) | 2 (1.4) | 0 (0.0) | 2 (1.4) | 0 (0.0) |
Hypotension | 18 (12.5) | 16 (11.1) | 2 (1.4) | 0 (0.0) | 11 (7.6) | 9 (6.2) | 2 (1.4) | 0 (0.0) |
Dizziness | 6 (4.2) | 6 (4.2) | 0 (0.0) | 0 (0.0) | 9 (6.2) | 9 (6.2) | 0 (0.0) | 0 (0.0) |
Note: ADRs, adverse drug reactions; AEs, adverse events.