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. 2022 Apr 8;216(8):385–387. doi: 10.5694/mja2.51488
Jurisdiction Recommendation Details Date Level of evidence Strength of recommendation
Latin America 18 Latin American consensus on management of residual cardiometabolic risk After myocardial infarction and patients with evidence of stable coronary disease, after treatment with statins, aspirin and ACEI/ARB June 2021 IIb B
Europe 19 Guidelines on cardiovascular disease prevention in clinical practice May be considered in secondary prevention of cardiovascular disease, particularly if other risk factors are insufficiently controlled or if recurrent cardiovascular disease events occur under optimal therapy September 2021 IIb A
Canada 20 Health Canada May be considered for the reduction of atherothrombotic events in adults with existing coronary heart disease in addition to standard therapies, including LDL cholesterol‐lowering and antithrombotic therapies August 2021

ACEI = angiotensin‐converting enzyme inhibitor; ARB = angiotensin II receptor antagonist; LDL = low‐density lipoprotein.