TABLE 3.
Results of the constrained (patient‐centric) optimization used to derive an abbreviated UMSARS
| UMSARS item | Slope (STD) | SCS | Rank | |
|---|---|---|---|---|
| Part I | ||||
| Swallowing a | UMSASR I, item 2 | 0.55 (0.17) | 3.30 | 3 |
| Handwriting | UMSARS I, item 3 | 0.36 (0.14) | 2.57 | 9 |
| Dressing a | UMSARS I, item 5 | 0.54 (0.30) | 1.78 | 16 |
| Hygiene a | UMSARS I, item 6 | 0.54 (0.38) | 1.42 | 21 |
| Walking a | UMSARS I, item 7 | 0.37 (0.21) | 1.74 | 17 |
| Orthostatic symptoms | UMSARS I, item 9 | 0.18 (0.12) | 1.50 | 20 |
| Urinary symptoms | UMSARS I, item 10 | 0.36 (0.30) | 1.21 | 22 |
| Bowel function | UMSARS I, item 12 | 0.26 (0.24) | 1.10 | 23 |
| Part II | ||||
| Facial expression | UMSARS II, item 1 | 0.55 (0.13) | 4.10 | 1 |
| Ocular motor dysfunction | UMSARS II, item 3 | 0.44 (0.21) | 2.04 | 14 |
| Action tremor | UMSARS II, item 5 | 0.24 (0.10) | 2.32 | 11 |
| Increased tone | UMSARS II, item 6 | 0.50 (0.15) | 3.31 | 2 |
| Rapid alternating movement hands | UMSARS II, item 7 | 0.44 (0.14) | 3.09 | 4 |
| Finger taps | UMSARS II, item 8 | 0.47 (0.17) | 2.79 | 6 |
| Leg agility | UMSARS II, item 9 | 0.51 (0.17) | 2.97 | 5 |
| Heel–knee–shin test | UMSARS II, item 10 | 0.63 (0.25) | 2.57 | 10 |
| Arising from chair | UMSARS II, item 11 | 0.65 (0.32) | 2.01 | 15 |
| Posture | UMSARS II, item 12 | 0.48 (0.17) | 2.78 | 7 |
| Gait a | UMSARS II, item 14 | 0.36 (0.13) | 2.77 | 8 |
Optimization procedure forced to include the patient‐centric items in the abbreviated scale. Slope indicates average estimate of the slope; rank indicates rank of item sensitivity to change, that is, highest ratio equals highest rank.
Abbreviations: UMSARS, Unified Multiple System Atrophy Rating Scale; STD, standard deviation of slope; SCS, sensitivity to change ratio (slope divided by standard deviation).
a
Patient‐centric item as identified by correlation analyses between single items of the UMSARS and quality‐of‐life scales.