Table 2. Top 20 candidate genes providing resistance and sensitivity.
| Fly Gene | Human ortholog | lfc | Fly Gene | Human ortholog | lfc |
|---|---|---|---|---|---|
| PEK | EIF2AK3 | 4.76 | pnt | ETS1 | -2.41 |
| Gfat2 | GFPT2 | 4.68 | Oscillin | GNPDA2 | -1.87 |
| CG9609 | GTF3A | 3.78 | upSET | KMT2E | -1.66 |
| Hrd3 | SEL1L | 3.71 | CG9590 | FAM114A2 | -1.37 |
| Ide | IDE | 3.25 | GalT1 | B3GALT1 | -1.31 |
| drongo | AGFG1 | 3.19 | Asx | ASXL3 | -1.18 |
| CG30345 | SLC46A1 | 3.17 | CG10984 | ANKRD12 | -1.17 |
| EcR | NR1H3 | 2.94 | Vap-33A | VAPB | -1.12 |
| ham | MECOM | 2.91 | Rab40 | RAB40C | -1.12 |
| srp | GATA1 | 2.72 | Cdk2 | CDK2 | -1.05 |
| sau | GOLPH3 | 2.53 | bel | DDX3X | -0.98 |
| Pten | PTEN | 2.52 | P5cr-2 | PYCR3 | -0.96 |
| Sin3A | SIN3A | 2.52 | Tango14 | NUS1 | -0.95 |
| Cdep | FARP2 | 2.37 | vtd | RAD21 | -0.95 |
| CG10960 | SLC2A8 | 2.16 | CG33110 | ELOVL1 | -0.95 |
| REG | PSME3 | 2.08 | CG32079 | SLC36A2 | -0.95 |
| dl | REL | 1.98 | Tor | MTOR | -0.94 |
| ND-MLRQ | NDUFA4 | 1.97 | Oatp58Da | SLCO1A2 | -0.93 |
| CG2926 | PHRF1 | 1.94 | dre4 | SUPT16H | -0.90 |
| Gpdh1 | GPD1 | 1.90 | sws | PNPLA7 | -0.90 |
Human orthologs are based on the highest DIOPT score [26].