Table 3. Comparison of the expression values of the 33 miRNAs selected between PCOS and controls.
| miRNA | PCOS | Control | p-value | P-value** |
|---|---|---|---|---|
| Mean±SD (n) | Mean±SD (n) | |||
| Let-7e-5p | 0.031±0.016 (9) | 0.065±0.24 (3) | 0.03 * | 0.37 |
| Let-7d-3p | 0.353±0.258 (12) | 0.477±0.187 (3) | 0.56* | 0.28 |
| miR-103a-3p | 0.021±0.016 (34) | 0.033±0.016 (13) | 0.01 * | 0.04 |
| miR127-3p | 0.005±0.004 (13) | 0.015±0.013 (4) | 0.05* | 0.05 |
| miR-199a-5p | 0.028±0.030 (20) | 0.065±0.053 (4) | 0.22* | 0.09 |
| miR-21-5p | 0.128±0.080 (36) | 0.085±0.070 (16) | 0.04 | 0.045 |
| miR-23a-3p | 0.166±0.171 (36) | 0.041±0.254 (16) | 0.0001 * | <0.0001 |
| miR-26a-5p | 0.692±0.465 (36) | 0.396±0.250 (16) | 0.02 | 0.03 |
| miR-29c-3p | 0.101±0.095 (9) | 0.224±0.066 (2) | 0.09* | 0.15 |
| miR-301a-3p | 0.007±0.008 (18) | 0.013±0.005 (3) | 0.16* | 0.08 |
| miR-324-3p | 0.017±0.027 (11) | 0.0002 (1) | 0.19* | 0.50 |
| miR-361-5p | 0.010±0.009 (31) | 0.020±0.012 (7) | 0.02 * | 0.03 |
| miR-376a-3p | 0.008±0.009 (36) | 0.015±0.006 (14) | 0.0004 * | 0.01 |
| miR-382-5p | 0.003±0.003 (13) | 0.015±0.011 (4) | 0.02 * | 0.02 |
| miR-433-3p | 0.016±0.013 (14) | 0.052±0.049 (4) | 0.06* | 0.003 |
| miR-128-3p | 0.002±0.002 (29) | 0.008±0.005 (5) | 0.003 * | 0.001 |
| miR-144-5p | 0.041±0.070 (4) | 0.124±0.093 (7) | 0.06* | 0.56 |
| miR-181b-5p | 0.014±0.021 (32) | 0.043±0.051(9) | 0.04 * | 0.01 |
| miR-18a-3p | 0.006±0.015 (18) | 0.008±0.0002 (2) | 0.08* | 0.75 |
| miR-192-5p | 0.200±0.226 (15) | 0.335±0.149 (3) | 0.21* | 0.36 |
| miR-197-3p | 13.237±10.303 (11) | 2.677±1.564 (6) | 0.02 * | 0.06 |
| miR-199a-3p | 0.279±0.030 (20) | 0.065±0.053 (4) | 0.22* | 0.09 |
| miR-19b-3p | 0.186±0.171 (34) | 1.088±1.046 (8) | 0.0001 * | <0.001 |
| miR-21-3p | 0.016±0.008 (10) | 0.038 (1) | 0.11* | 0.001 |
| miR-222-3p | 0.010±0.010 (35) | 0.018±0.011 (15) | 0.003 * | 0.01 |
| miR-28-3p | 0.013±0.013 (26) | 0.020±0.015 (7) | 0.12* | 0.11 |
| miR-33a-5p | 0.027±0.022 (17) | 0.066±0.027 (3) | 0.04 * | 0.02 |
| miR-483-5p | 0.021±0.018 (7) | 0.022 (1) | 0.83* | 0.70 |
| miR-494-3p | 0.004±0.005 (13) | 0.048 (1) | 0.11* | <0.001 |
| miR-505-3p | 0.007±0.009 (26) | 0.012±0.006 (4) | 0.10* | 0.37 |
| miR-584-5p | 1.482±1.324 (11) | 0.978±0.458 (4) | 0.79* | 0.50 |
| miR-660-5p | 0.008±0.019 (22) | 0.011±0.004 (2) | 0.14* | 0.73 |
| miR-885-5p | 0.009±0.010 (22) | 0.023±0.012 (3) | 0.05* | 0.01 |
Expression Values (2-ΔCT) normalized by the constitutive/housekeeping/endogenous miRNAs.
Data reported as mean±standard deviation.
Student T-test used for the analysis of normal distributed continuous data.
*Wilcoxon rank-sum test used for the analysis of non-normal distributed continuous data.
**p-value after controlling for BMI.