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. 2022 Oct 7;17(10):e0275267. doi: 10.1371/journal.pone.0275267

Table 4. Relations between Lnc THRIL and MiR-125b and clinical data in CD patients.

miR-125b Lnc THRIL
Median IQR P-value Median IQR P-value
Sex Female 0.31 0.27 0.78 0.002* 7.88 5.77 8.23 <0.001*
male 0.78 0.4 0.92 5.53 4.43 6.47
Smoker yes 0.69 0.22 0.96 0.693 5.87 4.43 7.21 0.510
no 0.67 0.31 0.78 5.9 4.67 7.97
Coffee consumption no 0.62 0.25 0.8 0.394 5.55 4.43 6.89 0.100
yes 0.74 0.4 0.83 6.02 4.81 7.97
Diabetes yes 0.74 0.7 0.8 0.720 2.07 2 2.13 <0.001*
no 0.67 0.3 0.83 5.95 4.76 7.88
Hypertension yes 0.37 0.35 0.4 0.518 5.21 5 5.42 0.438
no 0.7 0.3 0.83 5.95 4.57 7.88
Arthralgia yes 0.59 0.4 0.78 1.000 5.76 5.5 6.02 0.817
no 0.69 0.3 0.83 5.87 4.57 7.88
MSK yes 0.69 0.3 0.83 0.021* 8.12 5.42 9.01 0.066
no 0.30 0.19 0.35 5.82 4.56 7.54
Thromboembolic yes 0.78 0.31 0.83 0.007* 7.21 5.66 8.23 0.070
no 0.31 0.23 0.4 5.82 4.54 7.65
MC yes 0.78 0.31 0.83 0.585 5.55 4.54 7.65 0.383
no 0.78 0.4 0.92 5.95 5.46 7.9
Eye yes 0.4 0.25 0.78 0.363 5.82 4.65 7.5 0.912
no 0.71 0.47 1.26 5.87 4.57 7.88
Salicalyates yes 0.69 0.27 0.83 0.040* 5.23 4.5 7.06 0.166
no 0.81 0.4 0.94 6.02 4.76 8
Steroids yes 0.64 0.23 0.78 0.311 5.5 4.57 7.88 0.962
no 0.54 0.3 0.96 5.95 4.55 7.68
Azathioprine yes 0.7 0.27 0.78 0.214 5.97 4.57 7.65 0.959
no 0.66 0.4 0.96 5.87 4.76 7.88
Infliximab yes 0.69 0.3 0.78 0.456 5.79 4.67 7.39 0.978
no 0.78 0.43 0.85 5.87 4.43 7.93
Ileal strictures yes 0.78 0.78 0.96 0.098 5.87 4.76 6.47 0.946
no 0.59 0.3 0.78 5.9 4.57 7.88
Rectal fistula yes 0.81 0.64 0.96 0.002* 5.39 4.43 6.47 0.145
no 0.40 0.23 0.78 6.02 4.76 7.93
Perforation yes 1.08 0.76 1.53 0.001* 6.02 5.05 7.93 0.002*
no 0.54 0.27 0.78 4.27 3.28 5.1
Intestinal obstruction yes 0.78 0.31 0.83 0.562 4.55 4.11 7.93 0.152
no 0.64 0.3 0.78 6.02 5.05 7.65
Surgical resection yes 0.8 0.5 0.83 0.383 4.44 4.05 6.6 0.121
no 0.64 0.3 0.78 6.02 5.05 7.88
Colocutaneous fistula yes 0.57 0.33 0.78 0.578 5.9 3.95 7.23 0.853
no 0.69 0.3 0.83 5.87 4.57 7.88
Perianal abcess or fistula yes 0.45 0.12 0.78 0.229 6.11 4.33 7.88 0.779
no 0.69 0.31 0.83 5.87 4.76 7.65
Colonic stricture yes 0.17 0.12 0.23 0.002* 8.06 7.88 8.23 0.026*
no 0.74 0.31 0.83 5.77 4.57 7.43
Psoas abcess yes 0.74 0.22 0.83 0.959 4.11 2.13 8.44 0.188
no 0.67 0.31 0.8 5.95 4.88 7.77