TABLE 3.
Sensitivities and specificities of predictive scores and the ONES checklist for neural antibody positivity
| APE2 score | ACES score | APE2/ACES reflex score | ONES checklist | p a | |
|---|---|---|---|---|---|
| Sensitivity, % (95% CI) | 86 (67–100) | 64 (39–89) |
|
>.99 | |
| Specificity, % (95% CI) | 72 (62–82) | 90 (84–97) |
|
.18 | |
Abbreviations: ACES, Antibodies Contributing to Focal Epilepsy Signs and Symptoms; APE2, Antibody Prevalence in Epilepsy and Encephalopathy; CI, confidence interval; ONES, “Obvious” indications for Neural antibody testing in Epilepsy or Seizures.
a
Probability values are for comparisons of sensitivity and specificity of APE2/ACES reflex score to ONES checklist.