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Progesterone inhibits oxLDL‐induced trained immunity. Monocytes were trained with oxLDL (10 μg/ml) or RPMI for 24 h ± (A) progesterone, (B) cortisol, (C) dexamethasone, (D) β‐estradiol, or (E) DHT. Monocytes were then washed with PBS, rested for 5 days in culture media, and subsequently stimulated with LPS (10 ng/ml) for 24 h. Levels of TNFα and IL‐6 were measured in supernatants via ELISA. (Wilcoxon matched pairs signed rank test, n = 6, *p < 0.05)
