TABLE 1.

Patient demographics and characteristics (deceased CD and matched‐control CD cohorts)

Patient ID	Diagnosis	Histopathology	Sex	Age at diagnosis
Deceased CD group
1	UCD	Hyaline vascular	Male	13.5
2	iMCD	Hypervascular	Female	15.2
3	iMCD	Hypervascular	Male	17.0
4	iMCD	NS	Female	43.4
5	iMCD	Hypervascular	Female	65.5
6	iMCD	Hypervascular	Female	61.3
7	iMCD	Mixed	Male	66.7
8	POEMS‐associated MCD	Plasmacytic	Male	52.3
9	POEMS‐associated MCD	NS	Male	40.5
10	HHV8‐associated MCD	Plasmablastic	Female	80.8
Matched‐control CD cohort
11	UCD	Mixed	Male	48.5
12	UCD	NS	Female	19.0
13	iMCD	Hypervascular	Male	13.9
14	iMCD	Hypervascular	Female	21.7
15	iMCD	Hypervascular	Female	18.5
16	iMCD	Hypervascular	Male	2.6
17	iMCD	Mixed	Female	45.7
18	iMCD	Hypervascular	Female	39.8
19	iMCD	Hypervascular	Female	65.9
20	iMCD	Mixed	Male	47.6
21	iMCD	Hypervascular	Male	65.2
22	iMCD	Hypervascular	Female	40.3
23	iMCD	Plasmacytic	Female	53.7
24	iMCD	Mixed	Female	50.7
25	POEMS‐associated MCD	Mixed	Male	43.0
26	POEMS‐associated MCD	Mixed	Male	39.7
27	POEMS‐associated MCD	NS	Male	56.7
28	HHV8‐associated MCD	Plasmablastic	Male	68.1
29	HHV8‐associated MCD	Plasmablastic	Female	64.2

Abbreviations: CD, Castleman disease; HHV8, human herpesvirus 8; iMCD, idiopathic multicentric Castleman disease; NS, not stated; POEMS, polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes; UCD, unicentric Castleman disease.