TABLE 4.

Five‐year overall survival probability and adjusted hazard ratio for patients presented with clinically T1‐2, N0 parotid mucoepidermoid carcinoma in relation to demographic and clinical factors classified based on pathological features

Group	Factor	% 5‐year overall survival	HR a	95%CI	p‐value
No advanced pathological features	Age (year)
	<65	97.53	Reference
	≥65	86.15	4.58	2.77, 7.59	<0.001
	Sex
	Male	90.79	2.22	1.36, 3.60	0.001
	Female	95.99	Reference
	Charlson/Deyo score
	0	94.39	Reference
	1	92.00	1.33	0.75, 2.33	0.33
	≥2	90.81	1.46	0.45, 4.75	0.53
	Surgery
	Superficial parotidectomy	96.02	Reference
	Total parotidectomy	90.88	4.06	1.61, 10.26	0.003
	Facial nerve
	Preserved	94.82	Reference
	Sacrificed	91.90	1.56	0.92,2.65	0.10
	Elective neck dissection/adjuvant radiotherapy performed
	No/no	95.61	1.54	0.60, 3.90	0.37
	Yes/no	93.85	1.46	0.69, 3.12	0.32
	No/yes	89.35	2.42	0.78, 7.47	0.13
	Yes/yes	97.38	Reference
One or more advanced pathological features (poorly differentiated, T3‐4A, positive lymph node(s), positive surgical margins, lymphovascular invasion, extracapsular extension)	Age (year)
	<65	93.09	Reference
	≥65	65.12	6.13	3.59, 10.45	<0.001
	Sex
	Male	76.78	1.24	0.78, 1.96	0.37
	Female	86.60	Reference
	Charlson/Deyo score
	0	85.66	Reference
	1	67.58	1.47	0.86, 2.50	0.16
	≥2	77.00	2.96	1.24, 7.08	0.014
	Surgery
	Superficial parotidectomy	85.90	Reference
	Total parotidectomy	79.57	2.26	1.07, 4.78	0.034
	Facial nerve
	Preserved	85.75	Reference
	Sacrificed	79.88	1.20	0.75, 1.93	0.44
	Elective neck dissection/adjuvant radiotherapy performed
	No/no	87.50	1.19	0.52, 2.70	0.68
	Yes/no	81.32	1.41	0.82, 2.43	0.21
	No/yes	80.97	0.93	0.48, 1.77	0.82
	Yes/yes	86.00	Reference

Abbreviations: CI, confidence interval; HR, hazard ratio.

^a Multivariate Cox hazard ratio model includes all the variables in the table.