FIGURE 1.

The theoretical type 1 error rate of the classical allelic test, $T_{\text{allelic}}$. The nominal level is $\alpha =0.05$, departure from HWE is measured by $\delta =p_{AA}-p^2$, where p is the frequency of the minor allele A and $-p^2\le \delta \le p(1-p)$. When $p=0.5$, $-0.25\le \delta \le 0.25$