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. 2022 May 6;237(7):3001–3011. doi: 10.1002/jcp.30756

Figure 3.

Figure 3

Inflamed Crohn's mesentery MSCs/extracellular vesicles regulated THP‐1 polarization to have higher M1 expression. RT‐qPCR analysis of M1/M2 gene expression in THP‐1 cells following 8 h stimulation with MSCs/EVs. M1 markers CCL5 (b) and COX2 (d) gene expression. M2 markers MRC1 (c) and PPARy (a) gene expression. *p < 0.05. ME, mesentery​​​​​; MSC, mesenchymal stem cells; RT‐qPCR, quantitative reverse‐transcription polymerase chain reaction; SQ, subcutaneous.