TABLE 1.
CDX‐0159 healthy volunteer patient demographics
| CDX−0159 | Placebo (n = 8) | |||||
|---|---|---|---|---|---|---|
| 0.3 mg/kg (n = 6) | 1 mg/kg (n = 6) | 3 mg/kg (n = 6) | 9 mg/kg (n = 6) | Total (n = 24) | ||
| Age (median, range, years) | 29.5 (24–55) | 27.5 (26–44) | 39.5 (23–55) | 25.5 (20–53) | 29.0 (20–55) | 33.5 (24–51) |
| Gender | ||||||
| Female, N (%) | 2 (33%) | 4 (67%) | 3 (50%) | 3 (50%) | 12 (50%) | 4 (50%) |
| Male, N (%) | 4 (67%) | 2 (33%) | 3 (50%) | 3 (50%) | 12 (50%) | 4 (50%) |
| Race | ||||||
| White, N (%) | 2 (33%) | 3 (50%) | 6 (100%) | 1 (17%) | 12 (50%) | 1 (12%) |
| Black/African American, N (%) | 4 (67%) | 3 (50%) | 0 (0%) | 5 (83%) | 12 (50%) | 7 (88%) |
| Ethnicity | ||||||
| Not Hispanic or Latino | 6 (100%) | 6 (100%) | 6 (100%) | 6 (100%) | 24 (100%) | 8 (100%) |
| Weight (median, range, kg) | 79.0 (60.5–89.9) | 76.8 (55.1–95.4) | 74.3 (57.4–94.1) | 68.7 (59.7–85.8) | 76.0 (55.1 – 95.4) | 71.6 (62.0–84.7) |
| Baseline Tryptase Levels (median, range, ng/ml) | 3.9 (2–21.2) | 2.3 (1.8–3.8) | 3.8 (1.7–8.4) | 3.4 (1.9–4.7) | 3.4 (1.7–21.2) | 3.1 (1.9–6.7) |