Table 2.
Chemical derivatization reagent deposition techniques
| Technique | Advantages | Disadvantages |
|---|---|---|
| Acoustic multi‐spotter | Uniform, fast, good reproducibility | Droplet application |
| Electrospray deposition | Homogenous | Limited time for analyte–matrix interaction |
| Pneumatic Sprayer | Homogenous | Droplet size not constant |
| ImagePrep™ | Controlled conditions, automated, homogenous | Droplet size not constant, expensive |
| Dry‐coating | Cheap, high‐purity matrix | Poor analyte–matrix extraction |
| Sublimation | Homogenous, reproducible, fast | Poor analyte–matrix extraction |
| Desktop inkjet printer | Uniform droplets (multichannel) | Slow, solvent compatibility, clogging |