TABLE 2.

Changes in glycaemic indices from baseline to follow‐up visit

	Without cholecystectomy (n = 1564)	With cholecystectomy (n = 48)	P1	P2
∆ FPG subgroup			0.001
∆ < −10%, n (%)	436 (27.9)	11 (22.9)	0.45	0.65
−10% ≤ ∆ < 10%, n (%)	990 (63.3)	25 (52.1)	0.11	Reference
∆ ≥ 10%, n (%)	138 (8.8)	12 (25.0)	<0.001	0.02
∆ HbA1c subgroup			0.002
∆ < −10%, n (%)	63 (4.0)	1 (2.1)	0.76	0.49
−10% ≤ ∆ < 10%, n (%)	1133 (72.4)	25 (52.1)	0.002	Reference
∆ ≥ 10%, n (%)	368 (23.5)	22 (45.8)	<0.001	0.002
∆ TyG subgroup			0.22
∆ < −10%, n (%)	63 (4.0)	4 (8.3)	0.27	0.39
−10% ≤ ∆ < 10%, n (%)	1433 (91.6)	43 (89.6)	0.81	Reference
∆ ≥ 10%, n (%)	68 (4.3)	1 (2.1)	0.72	0.49
∆ SPISE subgroup			0.02
∆ < −10%, n (%)	368 (23.5)	7 (14.6)	0.15	0.58
−10% ≤ ∆ < 10%, n (%)	809 (51.7)	21 (43.8)	0.28	Reference
∆ ≥ 10%, n (%)	387 (24.7)	20 (41.7)	0.01	0.06

P1: Chi‐squared test or Fisher's exact test was used to compare the changes in glycaemic indices between the two groups.

P2: Multinomial logistic regression analyses were used to compare the changes in glycaemic indices between the two groups after adjusting for age, gender, change in body weight over the follow‐up, and baseline body mass index and glycaemic status.

Abbreviations: FPG, fasting plasma glucose; HbA1c, glycated haemoglobin; SPISE, single‐point insulin sensitivity estimator; TyG, triglyceride‐glucose index.