TABLE 7.
Characteristic | Tepper [19] | Ornello [23] | Raffaelli [24] | Lambru [21] | Scheffler [25] | Ranieri [26] | Robblee [27] | This audit |
---|---|---|---|---|---|---|---|---|
CM patients at baseline, n | 381 | 84 | 139 | 162 | 74 | 21 | 95 | 92 |
F, % | 87 | 88 | 84 | 83 | 80 | 90 | 89 | 79 |
Completed analysis, n | 375 | 76 | 45 | 100 | na | 21 | 39 | 72 |
Follow‐up duration, months | 3 | 6 | 3 | 3 | 3 | 3 | 6 | 3 |
Age, years | 42 | 47 | 54 | 46 | 46 | 44 | 49 | 46 |
Aura, % | 40 | 30 | 22 | 33 | na | na | 40 | 24 |
Medication overuse, % | 41 | 72 | na | 54 | 66 | 29 | 19 | 51 |
Previous botulinum toxin use, % | 67 | 49 | 100 | 91 | 100 | na | 83 | 47 |
Previous preventives, n | <3 | 88% tried 2–4 | 5 | 8 | >6 | >2 | 11 | 8 |
Baseline MHD/MMD/RxD, days | 21/18/9 | na/20/14 | 18/11/7 | 23/20/12 | 21/16/12 | 20/10/10 | 24/18/na | 28/15/12 |
Change in MHD/MMD/RxD, days | na/‐7/‐4 | na/‐15/‐8 | ‐5/‐5/‐6 | ‐6/‐6/‐3 | ‐6/‐5/‐3 | ‐9/‐6/‐6 | ‐7/‐9/na | 0/‐5/‐1 |
MMD 50% responder rate | 41 | 74 | na | 35 | 42 | na | 55 | 36 |
Constipation rate, % | 4 | 14 | 19 | 20 | 24 | 10 | 24 | 50 |
Abbreviations: CM, chronic migraine; F, female; MHD, monthly headache days; MMD, monthly migraine days; na, not available; RxD, acute treatment days.