Signalling questions	Description	Response options
1.1 Was the allocation sequence random?	The randomization schedule was generated by one of the authors (M.M.H.) using a program available online (http://www.randomization.com) Group assignment was concealed before randomization from participants and the study coordinators who enrolled them	Y
1.2 Was the allocation sequence concealed until participants were enrolled and assigned to interventions?		Y
1.3 Did baseline differences between intervention groups suggest a problem with the randomization process?	Baseline characteristics of study groups are shown in Table 1	N
Risk‐of‐bias judgement		Low

Note: N, No; Y, Yes.