TABLE 6.

Clinical trials with animals infected by the micro‐organisms for the three EO: T. vulgaris, C. zeylanicum and M. alternifolia

Animals	n	Location	Micro‐organism	EO	Action	Ref.
Male guinea pigs	55	Dermal	T. mentagrophytes sp.	C. zeylanicum	Complete cure at 9–11 days	(Ayatollahi Mousavi & Kazemi, 2015)
Mice	12	Oral	C. albicans	M. alternifolia	Protective activity	(Ninomiya et al., 2012)
Mice	6	Oral	C. albicans	M. alternifolia	Anti‐inflammatory action	(Ninomiya et al., 2013)
Mice	12	Oral	C. albicans	M. alternifolia	Reduced microscopic lesions	(Campos Rasteiro et al., 2014)
Rats	10	Vaginal	C. albicans	M. alternifolia	Removed infections	(Mondello et al., 2006)
Wistar rats	20	Dermal	T. rubrum T. mentagrophytes sp.	T. vulgaris	Complete cure at 8–20 days Anti‐inflammatory action	(Soković et al., 2008)

Abbreviations: EO, Essential Oil; n: sample size; Ref., References.