TABLE 2.
Liver biochemistry and transient elastography (TE) in 36 clinically stable MUL patients
| Normal value | 0–10 years (n = 10) | 11–20 years (n = 12) | ≥21 years (n = 14) | p | |
|---|---|---|---|---|---|
| TE, kPa | <7 | 6.0 (3.8–25.3) | 6.8 (4.0–26.1) | 9.7 (4.7–26.3) | .30 |
| Galactose t1/2, min | <12 | 9.5 (6.5–10.5) | 9.5 (7.5–12.5) | 10.0 (8.0–12.5) | .33 |
| APRI | <0.5 | 0.3 (0.2–0.6) | 0.3 (0.1–0.6) | 0.3 (0.2–1.2) | .74 |
| ALT, U/L | <35–50 a | 28 (18–43) | 32 (14–130) | 29.5 (13–67) | .65 |
| AST, U/L | <36–50 a | 44.5 (30–60) | 34 (20–53) | 33.5 (26–46) | .10 |
| GGT, U/L | <40–60 a | 16 (9–80) | 36 (12–128) | 33 (19–93) | .14 |
| Bilirubin, μmol/L | <20 | 7 (3–9) | 9.5 (5–31) | 10 (5–22) | .049 † |
| Bile acids, μmol/L | <6.0 | 4.4 (0.0–11.1) | 3.3 (0.0–6.6) | 3.7 (0.0–47.6) | .15 |
| TT, % | ≥70 | 104.5 (65–155) | 97 (55–136) | 108 (25–156) | .97 |
| Fibrinogen, g/L | ≥2 | 2.6 (1.9–4.5) | 3.0 (2.2–5.0) | 2.6 (2.2–3.3) | .41 |
| FV,% | ≥65 | 95 (83–143) | 109 (66–126) | 96.5 (47–128) | .61 |
| Albumin, g/L | ≥35–37 a | 40.9 (37.8–44.8) | 39.45 (36.5–44.7) | 41.55 (36.3–46.4) | .65 |
| Prealbumin, mg/L | ≥95–200 a | 190 (134–261) | 240.5 (167–429) | 233 (127–388) | .30 |
| Haemoglobin, g/L | ≥94–134 a | 123.5 (94–146) | 139.5 (124–172) | 152 (137–170) | .001 * |
| Leucocytes, E9/L | ≥3.4–6.0 a | 5.45 (4.3–15.0) | 6.15 (4.1–12.1) | 5.6 (4.0–6.6) | .80 |
| Thrombocytes, E9/L | ≥150–200 a | 261.5 (176–526) | 249 (183–361) | 232 (106–280) | .34 |
Note: Values are in median (range). Significant p values (<.05) are bolded.
a
Depending on age and/or gender.
*
Between first and third age group p = .001.
†
Between first and third age groups p = .040, between first and second groups p = .026.