TABLE 4.
Laboratory values and TE compared with signs of heart disease in 36 MUL patients
| Signs of restrictive physiology in echocardiography a | ProBNP above normal | |||||
|---|---|---|---|---|---|---|
| Present (n = 18) | Absent (n = 12) | p | Yes (n = 12) | No (n = 15) | p | |
| TE, kPa | 6.9 (4.0–26.1) | 5.4 (3.8–21.4) | .28 | 7.1 (4.5–25.3) | 6.6 (4.0–26.1) | .92 |
| Galactose t½, min | 9.5 (6.5–12.0) | 9.8 (8.0–12.5) | .44 | 9.5 (6.5–12.0) | 9.5 (7.5–12.5) | .85 |
| APRI | 0.3 (0.1–0.6) | 0.3 (0.2–0.6) | .67 | 0.3 (0.2–0.6) | 0.3 (0.1–0.6) | .92 |
| TT, % | 97 (55–136) | 126 (96–155) | .047 | 103 (65–116) | 113.5 (55–156) | .20 |
| Fibrinogen, g/L | 2.9 (2.2–5.0) | 2.4 (1.9–3.7) | .14 | 3.0 (1.9–4.5) | 2.65 (2.2–5.0) | .37 |
| ALT, U/L | 29 (13–57) | 29 (18–130) | .48 | 28.5 (13–57) | 28 (14–130) | .67 |
| AST, U/L | 35 (20–60) | 34.5 (29–53) | .64 | 39 (31–60) | 35 (20–53) | .39 |
| GGT, U/L | 24 (9–109) | 26 (12–128) | 1.00 | 24 (11–109) | 21.5 (9–128) | .88 |
| Bilirubin, μmol/L | 8 (3–31) | 10 (7–17) | .19 | 7 (3–21) | 8 (4–31) | .43 |
| Albumin, g/L | 41.2 (36.5–44.8) | 41.4 (37.4–46.4) | .37 | 41.4 (37.4–44.8) | 39.7 (36.5–46.4) | .60 |
| Factor V,% | 99 (66–130) | 112 (78–143) | .64 | 101 (83–130) | 113 (66–143) | .64 |
| Bile acids μmol/L | 3.4 (0.0–47.6) | 3.7 (2.6–6.6) | .54 | 3.4 (0.0–47.6) | 3.4 (0.0–11.1) | .80 |
| Prealbumin, mg/L | 219 (134–261) | 263 (190–429) | .07 | 190.5 (134–261) | 240.5 (190–429) | .031 |
| Haemoglobin, g/L | 131 (118–170) | 139 (94–172) | .34 | 144 (118–170) | 136 (123–172) | .91 |
| Leucocytes, E9/L | 5.6 (4.1–15.0) | 5.6 (4.5–11.0) | .49 | 5.6 (4.3–15.0) | 6.0 (4.1–11.0) | .73 |
| Thrombocytes, E9/L | 252 (152–526) | 236 (198–350) | 1.00 | 236 (152–526) | 254 (183–361) | .92 |
Note: Data presented as median (range). Significant p values are bolded.
a
Signs of restrictive physiology include impaired collapsing of inferior vena cava, retrograde flow of hepatic veins and breathing variation of tricuspid E wave exceeding 30%.