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. 2022 Jul 3;30(7):1401–1410. doi: 10.1002/oby.23467

TABLE 4.

Linear association between change in plasma C3 concentration and changes in plasma concentrations of biomarkers for endothelial dysfunction

Δ C3 (g/L)
95% CI p value
Δ Endothelial dysfunction score 2.500 (0.866 to 4.125) 0.003
Δ sE‐selectin (ng/mL) 83.00 (39.17 to 126.83) <0.001
Δ sICAM‐1 (ng/mL) 78.12 (36.94 to 119.29) <0.001
Δ vWF (%) 17.21 (−30.77 to 65.18) 0.474
Δ sVCAM‐1 (ng/mL) 29.00 (−67.11 to 125.11) 0.547

Note: Bold font represents statistically significant data. Crude unstandardized associations between change in plasma C3 and changes in plasma endothelial biomarkers. Results are shown for all men with obesity who participated in the intervention study (n = 49).

Abbreviations: sE‐selectin, soluble endothelial selectin; sICAM‐1, soluble intercellular adhesion molecule 1; sVCAM‐1, soluble vascular cell adhesion molecule 1; vWf, von Willebrand factor.