Table 2.
Antibiotic | Treatment start (h after inoculation) | Log10 reduction compared to | |
---|---|---|---|
Treatment start | Untreated endpoint | ||
Tobramycin | 0 | −/− | 2.6/1.85 |
3 | −/− | 0.37/0.36 | |
6 | −/− | −/− | |
Ciprofloxacin | 0 | 1.48/1.72 | 4.8/5 |
3 | 2.95/3.29 | 4.72/5.03 | |
6 | 0.89/0.48 | 1.29/0.63 | |
Penicillin | 0 | 1.39 | 4.71 |
3 | 2.17 | 3.93 | |
6 | 0.84 | 1.24 | |
Tobramycin + Ciprofloxacin | 0 | 3.91/3.46 | 7.23/6.74 |
3 | 3.07/3.05 | 4.83/4.79 | |
6 | 0.57/0.73 | 0.97/0.88 | |
Tobramycin + Penicillin | 0 | 2.61 | 5.94 |
3 | 2.63 | 4.4 | |
6 | 1.72 | 2.11 | |
Ciprofloxacin + Penicillin | 0 | 2.14 | 5.47 |
3 | 2.62 | 4.38 | |
6 | 2.19 | 2.59 |
Note:The means of the values displayed in Fig. 4A and B were calculated. Log10 CFU reductions of the treated samples were set in comparison with colony counts before treatment initiation and to untreated controls at the endpoint. Values seperated by a slash indicate the results for Fig. 4A/B. The “−” indicates no reduction.