TABLE 1.
Baseline characteristics of study cohort
| Overall | ACE | ARB | Beta Blocker | CCB | Thiazide Diuretic | |
|---|---|---|---|---|---|---|
| Characteristics | (n = 12 555) | (n = 5093) | (n = 1375) | (n = 2661) | (n = 1701) | (n = 1725) |
| sex = Female, n (%) | 6551 (52.2) | 2447 (48.0) | 687 (50.0) | 1395 (52.4) | 884 (52.0) | 1138 (66.0) |
| AMI, n (%) | 319 (2.5) | 79 (1.6) | 19 (1.4) | 164 (6.2) | 44 (2.6) | 13 (0.8) |
| Diabetes, n (%) | 2278 (18.1) | 1129 (22.2) | 283 (20.6) | 441 (16.6) | 256 (15.0) | 169 (9.8) |
| Heart failure, n (%) | 467 (3.7) | 126 (2.5) | 35 (2.5) | 208 (7.8) | 75 (4.4) | 23 (1.3) |
| Stroke, n (%) | 1085 (8.6) | 353 (6.9) | 102 (7.4) | 329 (12.4) | 203 (11.9) | 98 (5.7) |
| CKD, n (%) | 374 (3.0) | 109 (2.1) | 43 (3.1) | 112 (4.2) | 73 (4.3) | 37 (2.1) |
| BMI, mean (SD) | 28.4 (9.6) | 28.7 (9.7) | 28.8 (10.2) | 27.2 (9.4) | 28.0 (8.9) | 29.4 (9.6) |
| Diastolic BP, mean (SD) | 87.1 (11.5) | 88.1 (11.0) | 87.7 (11.5) | 85.0 (11.5) | 86.5 (12.4) | 87.2 (11.6) |
| Systolic BP, mean (SD) | 154.1 (14.3) | 154.5 (14.5) | 154.0 (14.4) | 152.6 (13.3) | 155.4 (14.7) | 154.0 (14.5) |
| Age, median [Q1,Q3] | 61.0 [56.0,67.0] | 60.0 [55.0,65.0] | 60.0 [55.0,66.0] | 62.0 [57.0,71.0] | 62.0 [56.0,71.0] | 60.0 [55.0,65.0] |
Note: Summaries are given for the overall cohort and for each treatment assignment arm.
Abbreviations: AMI, acute myocardial infarction; CKD, chronic kidney disease; BMI, body mass index; BP, blood pressure; eGFR, estimated glomerular filtration rate.