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miR‐378a directly targets NFKBIA/IκBα. (a) Wildtype (WT) and mutated (MUT) sequence of the putative miR‐378a binding site in the 3′UTR of NFKBIA. (b) Western blot analysis of IκBα upon overexpression (left) and inhibition (right) of miR‐378a. (c) The effect of miR‐378a on NFKBIA 3′UTR‐dependent luciferase activity in keratinocytes, identified by three independent experiments. **P < 0·01, ***P < 0·001 (Student’s two‐sided t‐test). [Colour figure can be viewed at wileyonlinelibrary.com]
