TABLE 3.

Association between microbial‐related factors and longitudinal naïve and activated T regulatory cells levels in the first year of life in the Treg cohort (n = 191)

	Naïve T regulatory cells*		Activated T regulatory cells*
	Mean difference (95% CI)	p value	Mean difference (95% CI)	p value
Prenatal Factors
Parental allergy history	−0.22 (−0.85, 0.41)	.49	−0.09 (−0.38, 0.21)	.57
Residents (3 or more)	0.67 (0.30, 1.04)	<.001	0.17 (0.05, 0.29)	.007
Pet dog	0.46 (0.10, 0.82)	.01	0.07 (−0.06, 0.20)	.30
Occupational social contact (mother)	0.16 (−0.21, 0.52)	.40	0.08 (−0.04, 0.21)	.20
Occupational social contact (father)	0.13 (−0.24, 0.50)	.49	0.03 (−0.11, 0.16)	.67

^* T regulatory cells as a % of CD4+ cells. Bold value indicate p<0.05 threshold.