Table 1.
EAS | EUR | Meta‐analysis (EAS + EUR) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Trait | Type | rg | SE | P‐value | rg | SE | P‐value | rg | SE | P‐value | q‐value |
Osteoporosis | Binary | 0.107 | 0.0784 | 0.173 | 0.0789 | 0.0439 | 0.0725 | 0.0856 | 0.0383 | 0.0254 | 0.377 |
Cirrhosis | Binary | 0.121 | 0.121 | 0.320 | 0.254 | 0.141 | 0.0719 | 0.178 | 0.0737 | 0.0538 | 0.377 |
Epilepsy | Binary | 0.140 | 0.126 | 0.268 | 0.141 | 0.0907 | 0.121 | 0.141 | 0.0920 | 0.0565 | 0.377 |
Prostate cancer | Binary | 0.0703 | 0.0510 | 0.168 | 0.0594 | 0.0614 | 0.333 | 0.0659 | 0.0392 | 0.0933 | 0.467 |
BMI | QTL | −0.0713 | 0.0294 | 0.0155 | −0.112 | 0.0178 | 2.80E−10 | −0.101 | 0.0152 | 2.97E−11 | 1.01E−09 |
CRP | QTL | −0.0363 | 0.0936 | 0.698 | −0.0772 | 0.0186 | 3.18E−05 | −0.0756 | 0.0182 | 3.40E−05 | 7.80E−05 |
HDL‐C | QTL | 0.122 | 0.0467 | 9.00E−03 | 0.0614 | 0.0218 | 4.90E−03 | 0.0722 | 0.0198 | 2.55E−04 | 2.90E−03 |
BS | QTL | −0.103 | 0.0475 | 0.0304 | −0.0588 | 0.0243 | 0.0154 | −0.0679 | 0.0216 | 1.70E−03 | 0.0144 |
TGs | QTL | −0.0510 | 0.0344 | 0.139 | −0.0529 | 0.0211 | 0.0121 | −0.0524 | 0.0180 | 3.60E−03 | 0.0244 |
SBP | QTL | −0.0694 | 0.0415 | 0.0943 | −0.0498 | 0.0225 | 0.0267 | −0.0543 | 0.0198 | 6.10E−03 | 0.0345 |
GGT | QTL | −9.10E−03 | 0.0343 | 0.791 | −0.0465 | 0.0203 | 0.0219 | −0.0368 | 0.0175 | 0.0352 | 0.171 |
DBP | QTL | −0.0345 | 0.0428 | 0.420 | −0.0385 | 0.0222 | 0.0834 | −0.0377 | 0.0197 | 0.0561 | 0.221 |
Phosphorus | QTL | 1.40E−03 | 0.0758 | 0.985 | 0.0460 | 0.0233 | 0.0483 | 0.0422 | 0.0223 | 0.0584 | 0.221 |
Lymphocyte count | QTL | −0.0545 | 0.0494 | 0.270 | 0.0449 | 0.0193 | 0.0198 | 0.0317 | 0.0180 | 0.0775 | 0.264 |
MCV | QTL | 0.0190 | 0.0343 | 0.580 | 0.0279 | 0.0174 | 0.109 | 0.0261 | 0.0155 | 0.0928 | 0.287 |
Bold numbers represent a significant correlation after applying false discovery rate correction.
BMI, body mass index; BS, blood sugar; CRP, C‐reactive protein; DBP, diastolic blood pressure; EAS, East Asian; EUR, European; GGT, γ‐glutamyl transferase; HDL‐C, high‐density lipoprotein cholesterol; MCV, mean corpuscular volume; QTL, quantitative trait loci; rg, genetic correlation; SBP, systolic blood pressure; SE, standard error; TGs, triglycerides; QTL, quantitative trait loci.