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. 2022 May 30;76(8):361–366. doi: 10.1111/pcn.13372

Table 1.

Results of genetic correlation analysis with P < 0.1

EAS EUR Meta‐analysis (EAS + EUR)
Trait Type rg SE P‐value rg SE P‐value rg SE P‐value q‐value
Osteoporosis Binary 0.107 0.0784 0.173 0.0789 0.0439 0.0725 0.0856 0.0383 0.0254 0.377
Cirrhosis Binary 0.121 0.121 0.320 0.254 0.141 0.0719 0.178 0.0737 0.0538 0.377
Epilepsy Binary 0.140 0.126 0.268 0.141 0.0907 0.121 0.141 0.0920 0.0565 0.377
Prostate cancer Binary 0.0703 0.0510 0.168 0.0594 0.0614 0.333 0.0659 0.0392 0.0933 0.467
BMI QTL −0.0713 0.0294 0.0155 −0.112 0.0178 2.80E−10 −0.101 0.0152 2.97E11 1.01E09
CRP QTL −0.0363 0.0936 0.698 −0.0772 0.0186 3.18E−05 −0.0756 0.0182 3.40E05 7.80E05
HDL‐C QTL 0.122 0.0467 9.00E−03 0.0614 0.0218 4.90E−03 0.0722 0.0198 2.55E04 2.90E03
BS QTL −0.103 0.0475 0.0304 −0.0588 0.0243 0.0154 −0.0679 0.0216 1.70E03 0.0144
TGs QTL −0.0510 0.0344 0.139 −0.0529 0.0211 0.0121 −0.0524 0.0180 3.60E03 0.0244
SBP QTL −0.0694 0.0415 0.0943 −0.0498 0.0225 0.0267 −0.0543 0.0198 6.10E03 0.0345
GGT QTL −9.10E−03 0.0343 0.791 −0.0465 0.0203 0.0219 −0.0368 0.0175 0.0352 0.171
DBP QTL −0.0345 0.0428 0.420 −0.0385 0.0222 0.0834 −0.0377 0.0197 0.0561 0.221
Phosphorus QTL 1.40E−03 0.0758 0.985 0.0460 0.0233 0.0483 0.0422 0.0223 0.0584 0.221
Lymphocyte count QTL −0.0545 0.0494 0.270 0.0449 0.0193 0.0198 0.0317 0.0180 0.0775 0.264
MCV QTL 0.0190 0.0343 0.580 0.0279 0.0174 0.109 0.0261 0.0155 0.0928 0.287

Bold numbers represent a significant correlation after applying false discovery rate correction.

BMI, body mass index; BS, blood sugar; CRP, C‐reactive protein; DBP, diastolic blood pressure; EAS, East Asian; EUR, European; GGT, γ‐glutamyl transferase; HDL‐C, high‐density lipoprotein cholesterol; MCV, mean corpuscular volume; QTL, quantitative trait loci; rg, genetic correlation; SBP, systolic blood pressure; SE, standard error; TGs, triglycerides; QTL, quantitative trait loci.