TABLE 1.

Characteristics of the study population, incidences and mortality data by diagnosis and sex

Study population	WKS	ARD	P‐value
All
Number	1149	2432
Person‐years followed up	9191	12,620
Number of deaths	645	1491
Mean age at diagnosis, mean (SD)	57 (9)	65 (9)	<0.001
Incidence/100,000 pyrs (95% CI)	2.4 (2.2–2.5)	5.0 (4.8–5.2)	<0.001
Crude mortality a , % (95% CI)	79.0 (74.1–83.4)	91.6 (85.1–96.0)	<0.001
Standardized mortality ratio (95% CI)	5.67 (5.25–6.13)	5.41 (5.14–5.70)	0.32
<65 years	7.32 (6.70–8.01)	8.12 (7.51–8.78)
65 years and over	3.46 (2.97–4.03)	4.37 (4.09–4.67)
Median survival time, years (95% CI)	10.7 (9.6–11.3)	5.9 (5.6–6.3)
Men
Number	841	1892
Person‐years followed up	6334	9584
Number of deaths	511	1199
Mean age at diagnosis, mean (SD)	57 (9)	65 (9)	<0.001
Incidence/100,000 pyrs (95% CI)	3.7 (3.4–3.9)	8.2 (7.9–8.6)	<0.001
Crude mortality*, % (95% CI)	85.2 (79.7–89.9)	92.2 (83.8–97.2)	<0.001
Standardized mortality ratio (95% CI)	5.58 (5.12–6.09)	5.16 (4.87–5.46)	0.13
<65 years	7.09 (6.41–7.84)	7.43 (6.80–8.11)
65 years and over	3.48 (2.94–4.13)	4.24 (3.93–4.56)
Median survival time, years (95% CI)	9.4 (8.3–10.5)	5.7 (5.3–6.0)
Women
Number	308	540
Person‐years followed up	2857	3037
Number of deaths	134	292
Mean age at diagnosis, mean (SD)	57 (9)	65 (9)	<0.001
Incidence/100,000 pyrs (95% CI)	1.2 (1.1–1.3)	2.1 (1.9–2.3)	<0.001
Crude mortality a , % (95% CI)	60.7 (52.3–69.3)	92.4 (81.1–98.2)	<0.001
Standardized mortality ratio (95% CI)	6.05 (5.11–7.17)	6.81 (6.07–7.34)	0.26
<65 years	8.41 (6.91–10.24)	13.06 (10.94–15.58)
65 years and over	3.37 (2.42–4.70)	5.05 (4.34–5.87)
Median survival time, years (95% CI)	14.3 (11.6–18.0)	7.3 (6.4–8.7)

^a At the end of the follow‐up period.

Abbreviations: ARD, alcohol‐related dementia; CI, confidence interval; pyrs, person‐years; SD, standard deviation; WKS, Wernicke‐Korsakoff syndrome.