Table 4.
Infections leading to hospitalization (inpatients only) among the general population and patients with any psoriasis
| IR per 100 000 person‐years among the general population (95% CI) | IR per 100 000 person‐years among patients with any psoriasis (95% CI) | IR differences per 100 000 person‐years (95% CI) | |
|---|---|---|---|
| Any infections (rare or severe) | 1531·8 (1520·6–1543·0) | 2005·1 (1973·0–2037·7) | 473·3 (452·4–494·7) |
| Serious infections | |||
| Any severe infections | 1529·7 (1518·5–1540·9) | 2001·8 (1969·7–2034·3) | 472·1 (451·2–493·4) |
| CNS infections | 17·32 (16·25–18·45) | 22·95 (20·06–26·26) | 5·64 (3·81–7·81) |
| URTI | 27·01 (25·67–28·42) | 35·99 (32·29–40·11) | 8·98 (6·63–11·69) |
| Pulmonary infections | 620·59 (613·94–627·31) | 780·45 (762·20–799·15) | 159·9 (148·3–171·8) |
| Heart infections | 29·04 (27·66–30·50) | 36·62 (32·92–40·74) | 7·58 (5·26–10·24) |
| GI infections | 354·08 (349·05–359·18) | 450·42 (436·57–464·72) | 96·34 (87·52–105·5) |
| UTI | 297·49 (292·91–302·13) | 379·82 (367·25–392·83) | 82·33 (74·34–90·70) |
| Gynaecological infections | 23·13 (21·39–25·01) | 27·03 (22·65–32·26) | 3·90 (1·26–7·25) |
| Musculoskeletal infections | 27·58 (26·23–29·00) | 43·11 (39·06–47·57) | 15·53 (12·84–18·57) |
| Skin and subcutaneous tissue infections | 107·76 (105·01–110·57) | 170·76 (162·34–179·63) | 63·00 (57·33–69·06) |
| Opportunistic infections | 46·34 (44·58–48·17) | 63·25 (58·30–68·61) | 16·91 (13·73–20·44) |
| Other infections | 140·97 (137·85–144·16) | 193·81 (184·92–203·13) | 52·84 (47·07–58·97) |
| Sepsis | 218·98 (215·11–222·93) | 302·6 (291·53–314·08) | 83·62 (76·42–91·15) |
| Rare | |||
| Any rare infections | 6·47 (5·83–7·18) | 8·47 (6·78–10·57) | 2·00 (0·95–3·39) |
| HIV | 0·85 (0·64–1·13) | 0·97 (0·51–1·87) | 0·13 (−0·13–0·74) |
| Hepatitis | 2·74 (2·34–3·22) | 4·34 (3·18–5·91) | 1·59 (0·84–2·69) |
| Tuberculosis | 3·01 (2·59–3·50) | 3·35 (2·36–4·77) | 0·34 (−0·23–1·26) |
CI, confidence interval; CNS, central nervous system; GI, gastrointestinal; IR, incidence rate; URTI, upper respiratory tract infections; UTI, urinary tract infections.