TABLE 6.
Adjusted associations between early eczema subclasses and early life allergic sensitization at 12 years as risk factors using early‐onset resolving as the reference category
| Allergic sensitization a | Early onset persistent [EOP] (59/619) |
|---|---|
| aOR (95% CI) b | |
| Sensitization at 6 months | |
| Allergic sensitization [n:455] | 3.41 (1.48–7.87) * |
| Aero sensitization [n:438] | 3.02 (1.00–9.10) |
| Food sensitization [n:455] | 3.57 (1.52–8.37) |
| Sensitization at 1 year | |
| Allergic sensitization [n:478] | 2.44 (1.00–5.92) |
| Aero sensitization [n:459] | 2.04 (0.70–5.98) |
| Food sensitization [n:475] | 4.35 (1.85–10.23) |
| Sensitization at 2 years | |
| Allergic sensitization [n:402] | 1.66 (0.70–3.94) |
| Aero sensitization [n:400] | 1.61 (0.70–3.71) |
| Food sensitization [n:391] | 3.66 (1.39–9.64) |
| Sensitization at 12 years | |
| Allergic sensitization [n:344] | 3.05 (0.84–11.05) |
| Aero sensitization [n:344] | 3.02 (0.84–10.92) |
| Food sensitization [n:331] | 1.45 (0.40–5.25) |
| Sensitization at 18 years | |
| Allergic sensitization [n:381] | 2.11 (0.63–7.04) |
| Aero sensitization [n:381] | 1.68 (0.55–5.14) |
| Food sensitization [n:374] | 5.10 (1.51–17.30) |
Abbreviations: 95% CI, 95% confidence interval; aMOR, adjusted multinomial odds ratio; n, number of observations in the regression model.
a
Reference category: Early onset resolving.
b
Adjusted for sex, parental eczema history, parental allergy history, parental education, parental occupation, Filaggrin null mutation, outdoor and indoor air pollution.
*
P‐values less than .05 are bolded.