Table 4.
Trends in age- and sex-standardized BZRA prescription rates among patients who received ≥3 BZRA prescriptions in 1 year between 2000 and 2019.
| Group |
2000 N = 7,209 |
2019 N = 24,962 |
Summary | Trend 1 | Trend 2 | Trend 3 | |||
|---|---|---|---|---|---|---|---|---|---|
| % | % | AAPC | Years | APC | Years | APC | Years | APC | |
| Prescriptions | |||||||||
| BZRA ≥ 3 | 34.9 | 42.4 | 0.3 (−1.0; 1.6) | 2000–2019 | 0.3 (−1.0; 1.6) | ||||
| Overall 18–44 | 4.6 | 4.9 | 1.7 (0.6; 2.9) | 2000–2014 | 3.0 (1.9; 4.0) | 2014–2019 | −1.7 (−5.3; 2.1) | ||
| Overall 45–64 | 14.0 | 14.0 | 0.7 (−0.3; 1.8) | 2000–2004 | 6.0 (0.9; 11.4) | 2004–2019 | –0.6 (–1.1; –0.1) | ||
| Overall 65+ | 16.4 | 23.5 | 1.9 (1.1; 2.8) | 2000–2006 | 8.2 (5.5; 11.0) | 2006–2019 | –0.8 (–1.4; –0.3) | ||
| Males | 11.4 | 14.2 | 0.5 (−1.0; 2.0) | 2000–2019 | 0.5 (−1.0; 2.0) | ||||
| Males 18–44 | 1.7 | 2.0 | 2.5 (0.9; 4.3) | 2000–2014 | 5.1 (3.6; 6.7) | 2014–2019 | −4.3 (−9.4; 1.0) | ||
| Males 45–64 | 4.3 | 4.8 | 1.0 (0.1; 1.8) | 2000–2009 | 3.6 (2.0; 5.2) | 2009–2019 | –1.3 (–2.3; –0.4) | ||
| Males 65+ | 5.3 | 7.3 | 1.6 (0.8; 2.3) | 2000–2007 | 6.4 (4.4; 8.6) | 2007–2019 | –1.2 (–1.8; –0.6) | ||
| Females | 23.6 | 28.2 | 0.5 (−1.3; 2.4) | 2000–2019 | 0.5 (−1.3; 2.4) | ||||
| Females 18–44 | 2.9 | 2.9 | 1.1 (0.5; 1.7) | 2000–2019 | 1.1 (0.5; 1.7) | ||||
| Females 45–64 | 9.7 | 9.2 | 0.2 (−1.3; 1.8) | 2000–2008 | 2.3 (0.5; 4.0) | 2008–2012 | −4.5 (−10.6; 2.0) | 2012–2019 | 0.7(−1.0; 2.4) |
| Females 65+ | 11.0 | 16.1 | 2.1 (1.2; 3.0) | 2000–2006 | 8.5 (5.6; 11.6) | 2006–2019 | –0.7 (–1.3; –0.1) | ||
AAPC, average annual percentage change; APC, average percentage change; statistically significant trends (95% CI) in bold.