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. 2022 Jul 23;188(10):2920–2931. doi: 10.1002/ajmg.a.62906

FIGURE 2.

FIGURE 2

Histologic exam of liver biopsy: macrovesicular steatosis with few portal‐inflammatory cells (HE. 10×); disturbed architecture due to porto‐portal fibrous septa (Masson trichrome stain, 10×); loss of biliary ducts (CK7 IHC, 10×) and increased Kupffer cells, sometimes with large leaf‐like cytoplasm (CD68 IHC, 20×).