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Authentic SARS-CoV-2 infection assay confirms the strong inhibition by the N-terminally extended HR2 peptide. Example images (A) and inhibition curve (B) from the infection of Caco-2+hACE2 cells by the Wuhan strain of SARS-CoV-2 in the presence of different concentrations of the longHR2_42 peptide. Nuclei are stained with Hoechst DNA dye (cyan), and infected cells are detected with an antibody specific for the viral N protein (magenta).
